POLARIZED SECRETION OF INTERLEUKIN (IL)-6 AND IL-8 BY HUMAN AIRWAY EPITHELIA 16HBE14O- CELLS IN RESPONSE TO CATIONIC POLYPEPTIDE CHALLENGE.

Polarized secretion of interleukin (IL)-6 and IL-8 by human airway epithelia 16HBE14o- cells in response to cationic polypeptide challenge.

BACKGROUND: The airway epithelium participates in asthmatic inflammation in many ways.Target cells of the epithelium can respond to a variety of inflammatory mediators and cytokines.Damage to the surface epithelium occurs following the secretion of eosinophil-derived, highly toxic cationic proteins.Moreover, the surface epithelium itself is respons

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Determination of population density of Aspergillus flavus and Aspergillus parasiticus in the last irrigation treatments before harvest in soil and fruits of pistachio trees

ObjectiveContamination of pistachio with Aspergillus and aflatoxin is one of the most important problems in the production and export of this valuable product.In this research, in addition to molecular identification of Aspergillus flavus and A.parasiticus and determination of the frequency of their toxigenic and atoxigenic isolates, the population

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SOX combined with tislelizumab and low-dose radiation therapy for the neoadjuvant treatment of locally advanced gastric/gastroesophageal junction adenocarcinoma: study protocol for a prospective, multicenter, single-arm, phase Ib/II clinical trial

BackgroundRecently, the clinical benefits of neoadjuvant chemotherapy combined with immunotherapy have been observed in patients with locally advanced gastric or gastroesophageal junction (G/GEJ) cancer; however, the pathological complete response (pCR) and long-term survival rates are still unsatisfactory.The aim of this study is to investigate th

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